Chen Xiao Chen, PhD, RN
Community & Health Systems
Nursing E415, Indianapolis
PhD, University of Wisconsin–Madison
MS, University of Wisconsin–Madison
MBBS, Tongji Medical College
Dr. Chen’s program of research focuses on management of dysmenorrhea. Characterized by menstrual pain, dysmenorrhea is a prevalent pain condition among women of reproductive age that puts women at higher risk for developing other chronic pain conditions later in life. Dr. Chen's goals for this program of research are to support dysmenorrhea management, improve women's quality of life, and to some extent, reduce the risk for developing future pain conditions among affected women. Dr. Chen uses biobehavioral approaches and integrates quantitative, qualitative, and big data. Specifically her team's work on dysmenorrhea entail (1) developing and evaluating symptom measurement tools, (2) identifying and characterizing dysmenorrhea phenotypes, (3) describing health behaviors (including health service uses, information seeking, and use of self-management strategies), and (4) exploring potential complementary alternative treatment for dysmenorrhea. These studies build toward the development of precision-based, personalized interventions to support dysmenorrhea management.
Beyond her research on dysmenorrhea, Dr. Chen has been engaged in interdisciplinary collaboration and mentoring in the areas of pain management, symptom science, and women’s health. Her areas of methodological expertise include advanced psychometrics, survey research, latent class analysis, and meta-analysis.
Indiana Clinical and Translational Sciences Institute KL2 Young Investigator Award in Clinical -Translational Research Program (KL2 TR002530 and UL1 TR002529, PI: Shekhar) (2018-2020)
T32 Postdoctoral Fellowship (T32 5T32NR007066-24, PI: Rawl), National Institute of Nursing Research (2016-2017).
Chen, C. X., Murphy, T., Ofner, S., Yahng, L., Krombach, P., LaPradd, M., Bakoyannis, G., & Carpenter, J. S. (2020). Development and Testing of the Dysmenorrhea Symptom Interference (DSI) Scale. Western Journal of Nursing Research, 193945920942252. Advance online publication. https://doi.org/10.1177/0193945920942252
Chen, C. X., Kroenke, K., Stump, T., Kean, J., Krebs, E. E., Bair, M. J., Damush, T., & Monahan, P. O. (2019). Comparative Responsiveness of the PROMIS Pain Interference Short Forms with Legacy Pain Measures: Results from Three Randomized Clinical Trials. The Journal of Pain, 20(6), 664–675. https://doi.org/10.1016/j.jpain.2018.11.010
Lovett, J., Gordon, C., Patton, S., & Chen, C. X. (2019). Online information on dysmenorrhea: An evaluation of readability, credibility, quality and usability. Journal of Clinical Nursing, 28(19-20), 3590–3598. https://doi.org/10.1111/jocn.14954
Lor, M., Oyesanya, T., Chen, C.X., Cherwin, C., & Moon, C. (2019). Postdoctoral opportunities for nursing PhD graduates: A resources guide. Western Journal of Nursing Research.41 (3): 459-476. https://doi.org/10.1177/0193945918775691
Chen, C. X., Groves, D., Miller, W. R., & Carpenter, J. S. (2018). Big Data and Dysmenorrhea: What Questions Do Women and Men Ask About Menstrual Pain? Journal of Women's Health (2002), 27(10), 1233–1241. https://doi.org/10.1089/jwh.2017.6732
Chen, C.X., Kroenke, K., Stump, T., Kean, J., Carpenter, J.S., Krebs, E., Bair, M., Damush, T., & Monahan, P. (2018). Estimating minimally important differences for the PROMIS pain interferences scales: results from three randomized clinical trials. PAIN: The Journal of the International Association for the Study of Pain. 159(4):775-782. http://dx.doi.org/10.1097/j.pain.0000000000001121
Chen, C.X., Draucker, C.B., & Carpenter, J.S. (2018). What women say about their dysmenorrhea: a qualitative thematic analysis. BMC Women’s Health 18 (1): 47. https://doi.org/10.1186/s12905-018-0538-8
Chen, C.X., Ofner, S., Bakoyannis G., Kwekkeboom, K.L.,& Carpenter, J.S. (2018). Symptoms-based phenotypes among women with dysmenorrhea: a latent class analysis. Western Journal of Nursing Research 40 (10):1452-1468. https://doi.org/10.1177/0193945917731778
Chen, C.X., Shieh, C., Draucker, C.B., & Carpenter, J.S. (2018). Reasons women do not seek care for dysmenorrhea. Journal of Clinical Nursing.27 (1-2): e301-e308. https://doi.org/10.1111/jocn.13946
Carpenter, J.S., Bakoyannis, G., Otte, J.L., Chen, C.X., Rand, K.L., Woods, N.F., Newton, K.M.., Joffe, H., Manson, J.E., Freeman, E.W., & Guthrie, K.A (2017). Validity, cutpoints, and minimally important differences for two hot flash related daily interference scales. Menopause. 24(8). 877-885. https://doi.org/10.1097/GME.0000000000000871
Chen, C.X., Kwekkeboom, K.L., & Ward, S.E. (2016). Beliefs about dysmenorrhea and their relationship to self-management. Research in Nursing & Health. 39(4):263-76. https://doi.org/10.1002/nur.21726
Chen, C.X., Barrett, B., & Kwekkeboom K.L. (2016). Efficacy of oral ginger for dysmenorrhea: a systematic review and meta-analysis. Evidence-Based Complementary and Alternative Medicine. 2016, 1-10. http://dx.doi.org/10.1155/2016/6295737
Chen, C.X., Kwekkeboom, K.L., & Ward, S.E. (2015). Self‐report pain and symptom measures for primary dysmenorrhoea: A critical review. European Journal of Pain, 19(3), 377-391. https://doi.org/10.1002/ejp.556
For a full list of publications, please visit